Cydectin (topical moxidectin)
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The primary resource for tackling feather mites as of 2022 can be found here, written by Marieke Brys (University of Ghent), where the use of topical moxidectin is recommended following an extensive study into feather mites in CPL horses. Cydectin pour-on 0.5% for cattle. At a dose of 1.5mg/kg body weight. 1ml of Cydectin contains 5mg of moxidectin. It was found conclusively to eradicate mites at the first application (second application is still recommended to catch the newly hatched eggs) with an unexpected but remarkable side effect of descaling hyperkeratosis from the legs over the following days and weeks.
If the weather is sunny when you need to apply Cydectin, your horse must stay out of the sun for 48 hours to avoid burning. This is because Cydectin is oily.
Consult your vet before use.
FAQ
Which Cydectin do I need?
Cydectin pour-on 0.5% for cattle
How/where do I apply it?
Using an oral syringe is easiest to draw up and dispense, below the knee and hock.
NEVER ON THE BACK/SPINE OF THE HORSE
Where can I get Cydectin from?
It is used off-license in equines (as are all mites treatments, including Dectomax injections) so you need a prescription from your vet
My vet is sceptical, what can I do?
Send them the study linked at the top of this page
Is it only sold in large amounts?
Yes, because it is sold for treating herds of livestock, in 1L and 2.5L bottles (perhaps the vet could buy a bottle for their own stock and dispense the appropriate amount?)
What is the treatment interval?
Short term (to catch newly hatched mites) 7-10 days
Long term, reinfestation was not noted within the recorded six month assessment period after initial application. It could last longer than that.
When is it not appropriate to use Cydectin?
Do not use on youngstock or very thin/malnourished horses
Do not turn the horse out in direct sun for 48 hours after application, because of the oily nature of the liquid
Do I have to stable my horse after application?
Only until it has dried onto the leg, or if the weather is rainy or sunny.
How long after application can I wash the legs?
Try to leave it as long as possible before washing, but 72 hours minimum.
Can I use it at the same time as an oral dewormer?
This may not be safe. Please consult your vet.
I am in the USA and we only have purple-staining Cydectin. How long does the stain last?
Members of the CPL Facebook group state that the purple stain only lasts 2-3 days
General considerations: wear appropriate PPE (personal protective equipment), gloves, patch test if necessary, beware horses can have individual sensitivities/reactions to any topical product.
Be aware of the environmental impact of mites treatments and use caution for local waterways and ecology. Dispose of packaging safely.
ALWAYS CONSULT YOUR VET.